Blockade of α1 subtype GABA(A) receptors attenuates the development of tolerance to the antinociceptive effects of midazolam in rats

Benzodiazepines bind to and act on α1–3 and α5-containing GABA(A) receptors. Previous studies suggest that different GABA(A) receptor α-subtypes mediate the various behavioral effects of benzodiazepines, which raises the possibility of combining benzodiazepines with subtype-selective GABA(A) recepto...

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Detaylı Bibliyografya
Yayımlandı:Behav Pharmacol
Asıl Yazarlar: Lewter, Lakeisha A., Golani, Lalit K, Cook, James M., Li, Jun-Xu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119291/
https://ncbi.nlm.nih.gov/pubmed/33290344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0000000000000614
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