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Blockade of α1 subtype GABA(A) receptors attenuates the development of tolerance to the antinociceptive effects of midazolam in rats
Benzodiazepines bind to and act on α1–3 and α5-containing GABA(A) receptors. Previous studies suggest that different GABA(A) receptor α-subtypes mediate the various behavioral effects of benzodiazepines, which raises the possibility of combining benzodiazepines with subtype-selective GABA(A) recepto...
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| Publicado no: | Behav Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8119291/ https://ncbi.nlm.nih.gov/pubmed/33290344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0000000000000614 |
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