GABA(A) receptor subtypes and the abuse-related effects of ethanol in rhesus monkeys: Experiments with selective positive allosteric modulators

BACKGROUND: Previous studies have investigated α1GABA(A) and α5GABA(A) receptor mechanisms in the behavioral effects of ethanol in monkeys. However, genetic studies in humans and preclinical studies with mutant mice suggest a role for α2GABA(A) and/or α3GABA(A) receptors in the effects of ethanol. T...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Berro, Lais F., Rüedi-Bettschen, Daniela, Cook, Jemma E., Golani, Lalit K., Li, Guanguan, Jahan, Rajwana, Rashid, Farjana, Cook, James M., Rowlett, James K., Platt, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601614/
https://ncbi.nlm.nih.gov/pubmed/30861153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14000
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