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Epigenome-wide association study of lung function level and its change

Previous reports link differential DNA methylation (DNAme) to environmental exposures that are associated with lung function. Direct evidence on lung function DNAme is, however, limited. We undertook an agnostic epigenome-wide association study (EWAS) on pre-bronchodilation lung function and its cha...

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Vydáno v:Eur Respir J
Hlavní autoři: Imboden, Medea, Wielscher, Matthias, Rezwan, Faisal I., Amaral, André F.S., Schaffner, Emmanuel, Jeong, Ayoung, Beckmeyer-Borowko, Anna, Harris, Sarah E., Starr, John M., Deary, Ian J., Flexeder, Claudia, Waldenberger, Melanie, Peters, Annette, Schulz, Holger, Chen, Su, Sunny, Shadia Khan, Karmaus, Wilfried J.J., Jiang, Yu, Erhart, Gertraud, Kronenberg, Florian, Arathimos, Ryan, Sharp, Gemma C., Henderson, Alexander John, Fu, Yu, Piirilä, Päivi, Pietiläinen, Kirsi H., Ollikainen, Miina, Johansson, Asa, Gyllensten, Ulf, de Vries, Maaike, van der Plaat, Diana A., de Jong, Kim, Boezen, H. Marike, Hall, Ian P., Tobin, Martin D., Jarvelin, Marjo-Riitta, Holloway, John W., Jarvis, Deborah, Probst-Hensch, Nicole M.
Médium: Artigo
Jazyk:Inglês
Vydáno: European Respiratory Society 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610463/
https://ncbi.nlm.nih.gov/pubmed/31073081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00457-2019
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