Epigenome-wide association study of lung function level and its change

Previous reports link differential DNA methylation (DNAme) to environmental exposures that are associated with lung function. Direct evidence on lung function DNAme is, however, limited. We undertook an agnostic epigenome-wide association study (EWAS) on pre-bronchodilation lung function and its cha...

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Publicat a:Eur Respir J
Autors principals: Imboden, Medea, Wielscher, Matthias, Rezwan, Faisal I., Amaral, André F.S., Schaffner, Emmanuel, Jeong, Ayoung, Beckmeyer-Borowko, Anna, Harris, Sarah E., Starr, John M., Deary, Ian J., Flexeder, Claudia, Waldenberger, Melanie, Peters, Annette, Schulz, Holger, Chen, Su, Sunny, Shadia Khan, Karmaus, Wilfried J.J., Jiang, Yu, Erhart, Gertraud, Kronenberg, Florian, Arathimos, Ryan, Sharp, Gemma C., Henderson, Alexander John, Fu, Yu, Piirilä, Päivi, Pietiläinen, Kirsi H., Ollikainen, Miina, Johansson, Asa, Gyllensten, Ulf, de Vries, Maaike, van der Plaat, Diana A., de Jong, Kim, Boezen, H. Marike, Hall, Ian P., Tobin, Martin D., Jarvelin, Marjo-Riitta, Holloway, John W., Jarvis, Deborah, Probst-Hensch, Nicole M.
Format: Artigo
Idioma:Inglês
Publicat: European Respiratory Society 2019
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610463/
https://ncbi.nlm.nih.gov/pubmed/31073081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00457-2019
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