SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts

BACKGROUND: The pathophysiological role of SERPINA1 in respiratory health may be more strongly determined by the regulation of its expression than by common genetic variants. A family based study of predominantly smoking adults found methylation at two Cytosine-phosphate-Guanine sites (CpGs) in SERP...

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Detalhes bibliográficos
Publicado no:Respir Res
Principais autores: Beckmeyer-Borowko, Anna, Imboden, Medea, Rezwan, Faisal I., Wielscher, Matthias, Amaral, Andre F. S., Jeong, Ayoung, Schaffner, Emmanuel, Auvinen, Juha, Sebert, Sylvain, Karhunen, Ville, Bettschart, Robert, Turk, Alexander, Pons, Marco, Stolz, Daiana, Kronenberg, Florian, Arathimos, Ryan, Sharp, Gemma C., Relton, Caroline, Henderson, Alexander J., Jarvelin, Marjo-Riitta, Jarvis, Deborah, Holloway, John W., Probst-Hensch, Nicole M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103990/
https://ncbi.nlm.nih.gov/pubmed/30134983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0850-8
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