SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts

BACKGROUND: The pathophysiological role of SERPINA1 in respiratory health may be more strongly determined by the regulation of its expression than by common genetic variants. A family based study of predominantly smoking adults found methylation at two Cytosine-phosphate-Guanine sites (CpGs) in SERP...

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Bibliografske podrobnosti
izdano v:Respir Res
Main Authors: Beckmeyer-Borowko, Anna, Imboden, Medea, Rezwan, Faisal I., Wielscher, Matthias, Amaral, Andre F. S., Jeong, Ayoung, Schaffner, Emmanuel, Auvinen, Juha, Sebert, Sylvain, Karhunen, Ville, Bettschart, Robert, Turk, Alexander, Pons, Marco, Stolz, Daiana, Kronenberg, Florian, Arathimos, Ryan, Sharp, Gemma C., Relton, Caroline, Henderson, Alexander J., Jarvelin, Marjo-Riitta, Jarvis, Deborah, Holloway, John W., Probst-Hensch, Nicole M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103990/
https://ncbi.nlm.nih.gov/pubmed/30134983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0850-8
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