Loading...

BRCA1 regulates the cancer stem cell fate of breast cancer cells in the context of hypoxia and histone deacetylase inhibitors

Cancer cell stemness is essential for enabling malignant progression and clonal evolution. Cancer cell fate is likely determined by complex mechanisms involving both cell-intrinsic pathways and stress signals from tumor microenvironment. In this study, we examined the role of the tumor suppressor BR...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Kim, Hoon, Lin, Qun, Yun, Zhong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609720/
https://ncbi.nlm.nih.gov/pubmed/31273285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46210-y
Tags: Add Tag
No Tags, Be the first to tag this record!