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The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells

BACKGROUND: Tumor hypoxia is an independent prognostic factor associated with poor patient survival. Emerging evidence suggests that hypoxia can potentially maintain or enhance the stem cell phenotype of both normal stem cells and cancer cells. However, it remains to be determined whether cell fate...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res
Main Authors: Kim, Hoon, Lin, Qun, Glazer, Peter M., Yun, Zhong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840770/
https://ncbi.nlm.nih.gov/pubmed/29510720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-0944-8
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