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The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells

BACKGROUND: Tumor hypoxia is an independent prognostic factor associated with poor patient survival. Emerging evidence suggests that hypoxia can potentially maintain or enhance the stem cell phenotype of both normal stem cells and cancer cells. However, it remains to be determined whether cell fate...

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Bibliografische gegevens
Gepubliceerd in:Breast Cancer Res
Hoofdauteurs: Kim, Hoon, Lin, Qun, Glazer, Peter M., Yun, Zhong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840770/
https://ncbi.nlm.nih.gov/pubmed/29510720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-0944-8
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