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The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells

BACKGROUND: Tumor hypoxia is an independent prognostic factor associated with poor patient survival. Emerging evidence suggests that hypoxia can potentially maintain or enhance the stem cell phenotype of both normal stem cells and cancer cells. However, it remains to be determined whether cell fate...

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Bibliografske podrobnosti
izdano v:Breast Cancer Res
Main Authors: Kim, Hoon, Lin, Qun, Glazer, Peter M., Yun, Zhong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840770/
https://ncbi.nlm.nih.gov/pubmed/29510720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-0944-8
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