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The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells

BACKGROUND: Tumor hypoxia is an independent prognostic factor associated with poor patient survival. Emerging evidence suggests that hypoxia can potentially maintain or enhance the stem cell phenotype of both normal stem cells and cancer cells. However, it remains to be determined whether cell fate...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Kim, Hoon, Lin, Qun, Glazer, Peter M., Yun, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840770/
https://ncbi.nlm.nih.gov/pubmed/29510720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-0944-8
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