SPARC gene deletion protects against toxic liver injury and is associated to an enhanced proliferative capacity and reduced oxidative stress response

SPARC, also known as osteonectin and BM-40, is a matricellular protein with a number of biological functions. Hepatic SPARC expression is induced in response to thioacetamide, bile-duct ligation, and acute injuries such as concanavalin A and lipopolysacharide (LPS)/D-galactosamine. We have previousl...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Peixoto, Estanislao, Atorrasagasti, Catalina, Malvicini, Mariana, Fiore, Esteban, Rodriguez, Marcelo, Garcia, Mariana, Finocchieto, Paola, Poderoso, Juan J., Corrales, Fernando, Mazzolini, Guillermo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609249/
https://ncbi.nlm.nih.gov/pubmed/31289615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9456
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