SPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β(1) and PDGF

Liver fibrosis is an active process that involves changes in cell-cell and cell-extracellular matrix (ECM) interaction. Secreted protein, acidic and rich in cysteine (SPARC) is an ECM protein with many biological functions that is overexpressed in cirrhotic livers and upregulated in activated hepati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Atorrasagasti, Catalina, Aquino, Jorge B., Hofman, Leonardo, Alaniz, Laura, Malvicini, Mariana, Garcia, Mariana, Benedetti, Lorena, Friedman, Scott L., Podhajcer, Osvaldo, Mazzolini, Guillermo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2011
Gaiak:
Liver and Biliary Tract
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094149/
https://ncbi.nlm.nih.gov/pubmed/21311029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00316.2010
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