SPARC expression is associated with hepatic injury in rodents and humans with non-alcoholic fatty liver disease

Mechanisms that control progression from simple steatosis to steato-hepatitis and fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) are unknown. SPARC, a secreted matricellular protein, is over-expressed in the liver under chronic injury. Contribution of SPARC accumulation to disea...

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Publicado no:Sci Rep
Main Authors: Mazzolini, Guillermo, Atorrasagasti, Catalina, Onorato, Agostina, Peixoto, Estanislao, Schlattjan, Martin, Sowa, Jan-Peter, Sydor, Svenja, Gerken, Guido, Canbay, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768809/
https://ncbi.nlm.nih.gov/pubmed/29335425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18981-9
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