Anti-Factor H Antibody Reactivity in Young Adults Vaccinated with a Meningococcal Serogroup B Vaccine Containing Factor H Binding Protein

Meningococcal serogroup B (MenB) vaccines contain recombinant factor H binding protein (FHbp), which can complex with complement factor H (CFH) and thereby risk eliciting anti-FH autoantibodies. While anti-FH antibodies can be present in sera of healthy persons, the antibodies are implicated in auto...

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Publicado no:mSphere
Main Authors: Sharkey, Kelsey, Beernink, Peter T., Langley, Joanne M., Gantt, Soren, Quach, Caroline, Dold, Christina, Liu, Qin, Galvan, Manuel, Granoff, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609231/
https://ncbi.nlm.nih.gov/pubmed/31270173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00393-19
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