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Effect of Complement Factor H on anti-FHbp Serum Bactericidal Antibody Responses of Infant Rhesus Macaques Boosted with a Licensed Meningococcal Serogroup B Vaccine

FHbp is a major serogroup B meningococcal vaccine antigen. Binding of complement Factor H (FH) to FHbp is specific for human and some non-human primate FH. In previous studies, FH binding to FHbp vaccines impaired protective anti-FHbp antibody responses. In this study we investigated anti-FHbp antib...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Giuntini, Serena, Beernink, Peter T., Granoff, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684420/
https://ncbi.nlm.nih.gov/pubmed/26562320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.10.135
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