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Probing α(4)βδ GABA(A) Receptor Heterogeneity: Differential Regional Effects of a Functionally Selective α(4)β(1)δ/α(4)β(3)δ Receptor Agonist on Tonic and Phasic Inhibition in Rat Brain
In the present study, the orthosteric GABA(A) receptor (GABA(A)R) ligand 4,5,6,7-tetrahydroisothiazolo[5,4-c]pyridin-3-ol (Thio-THIP) was found to possess a highly interesting functional profile at recombinant human GABA(A)Rs and native rat GABA(A)Rs. Whereas Thio-THIP displayed weak antagonist acti...
में बचाया:
| में प्रकाशित: | J Neurosci |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Society for Neuroscience
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6608486/ https://ncbi.nlm.nih.gov/pubmed/25471566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1495-14.2014 |
| टैग : |
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