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Elucidation of Molecular Impediments in the α6 Subunit for in Vitro Expression of Functional α6β4* Nicotinic Acetylcholine Receptors

Explorations into the α6-containing nicotinic acetylcholine receptors (α6* nAChRs) as putative drug targets have been severely hampered by the inefficient functional expression of the receptors in heterologous expression systems. In this study, the molecular basis for the problem was investigated th...

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Detaylı Bibliyografya
Asıl Yazarlar: Jensen, Anne B., Hoestgaard-Jensen, Kirsten, Jensen, Anders A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837116/
https://ncbi.nlm.nih.gov/pubmed/24085295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.509356
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