Distinct contributions of nicotinic acetylcholine receptor subunit α4 and subunit α6 to the reinforcing effects of nicotine

Nicotine is the primary psychoactive component of tobacco. Its reinforcing and addictive properties depend on nicotinic acetylcholine receptors (nAChRs) located within the mesolimbic axis originating in the ventral tegmental area (VTA). The roles and oligomeric assembly of subunit α4- and subunit α6...

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Detalles Bibliográficos
Autores principales: Exley, Richard, Maubourguet, Nicolas, David, Vincent, Eddine, Raphaël, Evrard, Alexis, Pons, Stéphanie, Marti, Fabio, Threlfell, Sarah, Cazala, Pierre, McIntosh, J. Michael, Changeux, Jean-Pierre, Maskos, Uwe, Cragg, Stephanie J., Faure, Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088627/
https://ncbi.nlm.nih.gov/pubmed/21502501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103000108
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