Distinct contributions of nicotinic acetylcholine receptor subunit α4 and subunit α6 to the reinforcing effects of nicotine

Nicotine is the primary psychoactive component of tobacco. Its reinforcing and addictive properties depend on nicotinic acetylcholine receptors (nAChRs) located within the mesolimbic axis originating in the ventral tegmental area (VTA). The roles and oligomeric assembly of subunit α4- and subunit α6...

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Detalhes bibliográficos
Main Authors: Exley, Richard, Maubourguet, Nicolas, David, Vincent, Eddine, Raphaël, Evrard, Alexis, Pons, Stéphanie, Marti, Fabio, Threlfell, Sarah, Cazala, Pierre, McIntosh, J. Michael, Changeux, Jean-Pierre, Maskos, Uwe, Cragg, Stephanie J., Faure, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088627/
https://ncbi.nlm.nih.gov/pubmed/21502501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103000108
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