Distinct contributions of nicotinic acetylcholine receptor subunit α4 and subunit α6 to the reinforcing effects of nicotine

Nicotine is the primary psychoactive component of tobacco. Its reinforcing and addictive properties depend on nicotinic acetylcholine receptors (nAChRs) located within the mesolimbic axis originating in the ventral tegmental area (VTA). The roles and oligomeric assembly of subunit α4- and subunit α6...

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Bibliografski detalji
Glavni autori: Exley, Richard, Maubourguet, Nicolas, David, Vincent, Eddine, Raphaël, Evrard, Alexis, Pons, Stéphanie, Marti, Fabio, Threlfell, Sarah, Cazala, Pierre, McIntosh, J. Michael, Changeux, Jean-Pierre, Maskos, Uwe, Cragg, Stephanie J., Faure, Philippe
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088627/
https://ncbi.nlm.nih.gov/pubmed/21502501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103000108
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