Tonic Inhibition of Accumbal Spiny Neurons by Extrasynaptic α4βδ GABA(A) Receptors Modulates the Actions of Psychostimulants

Within the nucleus accumbens (NAc), synaptic GABA(A) receptors (GABA(A)Rs) mediate phasic inhibition of medium spiny neurons (MSNs) and influence behavioral responses to cocaine. We demonstrate that both dopamine D1- and D2-receptor-expressing MSNs (D-MSNs) additionally harbor extrasynaptic GABA(A)R...

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Hauptverfasser: Maguire, Edward P., Macpherson, Tom, Swinny, Jerome D., Dixon, Claire I., Herd, Murray B., Belelli, Delia, Stephens, David N., King, Sarah L., Lambert, Jeremy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891962/
https://ncbi.nlm.nih.gov/pubmed/24431441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3232-13.2014
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