Immune-Induced Fever Is Mediated by IL-6 Receptors on Brain Endothelial Cells Coupled to STAT3-Dependent Induction of Brain Endothelial Prostaglandin Synthesis

The cytokine IL-6, which is released upon peripheral immune challenge, is critical for the febrile response, but the mechanism by which IL-6 is pyrogenic has remained obscure. Here we generated mice with deletion of the membrane bound IL-6 receptor α (IL-6Rα) on neural cells, on peripheral nerves, o...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Eskilsson, Anna, Mirrasekhian, Elahe, Dufour, Sylvie, Schwaninger, Markus, Engblom, David, Blomqvist, Anders
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608482/
https://ncbi.nlm.nih.gov/pubmed/25429137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3520-14.2014
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars