Immune-Induced Fever Is Dependent on Local But Not Generalized Prostaglandin E(2) Synthesis in the Brain

Fever occurs upon binding of prostaglandin E(2) (PGE(2)) to EP(3) receptors in the median preoptic nucleus of the hypothalamus, but the origin of the pyrogenic PGE(2) has not been clearly determined. Here, using mice of both sexes, we examined the role of local versus generalized PGE(2) production i...

詳細記述

保存先:
書誌詳細
出版年:J Neurosci
主要な著者: Eskilsson, Anna, Matsuwaki, Takashi, Shionoya, Kiseko, Mirrasekhian, Elahe, Zajdel, Joanna, Schwaninger, Markus, Engblom, David, Blomqvist, Anders
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2017
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596481/
https://ncbi.nlm.nih.gov/pubmed/28438967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3846-16.2017
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