Stimulation of δ Opioid Receptor and Blockade of Nociceptin/Orphanin FQ Receptor Synergistically Attenuate Parkinsonism

δ opioid peptide (DOP) receptors are considered a therapeutic target in Parkinson's disease, although the use of DOP agonists may be limited by side effects, including convulsions. To circumvent this issue, we evaluated whether blockade of nociceptin/orphanin FQ (N/OFQ) tone potentiated the ant...

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Vydáno v:J Neurosci
Hlavní autoři: Mabrouk, Omar S., Viaro, Riccardo, Volta, Mattia, Ledonne, Ada, Mercuri, Nicola, Morari, Michele
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608339/
https://ncbi.nlm.nih.gov/pubmed/25253844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4677-13.2014
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