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TGF‐β inhibits IL‐7‐induced proliferation in memory but not naive human CD4(+) T cells

TGF‐β is a potent suppressor of T cell activation and expansion. Although the antiproliferative effects of TGF‐β are well characterized in TCR‐activated cells, the effects of TGF‐β on T cell proliferation driven by homeostatic cytokines, such as IL‐7, are poorly defined. In the current study, we fou...

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Detalles Bibliográficos
Publicado en:J Leukoc Biol
Autores principales: Nguyen, Thao P., Sieg, Scott F.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608080/
https://ncbi.nlm.nih.gov/pubmed/28588029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A1216-520RR
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