IL‐27 enhances LPS‐induced IL‐1β in human monocytes and murine macrophages

IL‐27 bridges innate and adaptive immunity by modulating cytokine production from myeloid cells and regulating Th cell differentiation. During bacterial infection, TLR4 triggering by LPS induces IL‐27 production by monocytes and macrophages. We have previously shown that IL‐27 can prime monocytes fo...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Petes, Carlene, Wynick, Christopher, Guzzo, Christina, Mehta, Divya, Logan, Sarah, Banfield, Bruce W., Basta, Sameh, Cooper, Andrea, Gee, Katrina
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608054/
https://ncbi.nlm.nih.gov/pubmed/28377398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0316-098R
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