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CXCR4 knockdown prevents inflammatory cytokine expression in macrophages by suppressing activation of MAPK and NF-κB signaling pathways

BACKGROUND: Recent evidence has shown that C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in acute lung injury (ALI). Macrophages are key factors in the pathogenesis of ALI. The aim of this study was to investigate the role of CXCR4 in macrophages after lipopolysaccharide (LPS) stimula...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Tian, Xue, Xie, Guogang, Xiao, Hui, Ding, Fengming, Bao, Wuping, Zhang, Min
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607528/
https://ncbi.nlm.nih.gov/pubmed/31304005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-019-0315-x
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