SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-κB pathways in RAW 264.7 macrophages

AIM: To elucidate the anti-inflammatory potentials and underlying mechanisms of SM905, a novel artemisinin derivative, in lipopolysaccharide (LPS)-stimulated murine macrophage RAW 264.7 cells. METHODS: Nitric oxide (NO) generation, cytokine production, and the protein expression levels of inducible...

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Detalhes bibliográficos
Main Authors: Wang, Jun-xia, Hou, Li-fei, Yang, Yang, Tang, Wei, Li, Ying, Zuo, Jian-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007329/
https://ncbi.nlm.nih.gov/pubmed/19801997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.138
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