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Recombinant CC16 protein inhibits the production of pro-inflammatory cytokines via NF-κB and p38 MAPK pathways in LPS-activated RAW264.7 macrophages

Accumulating evidence indicates that Clara cell protein-16 (CC16) has anti-inflammatory functions, although the involved molecular pathways have not been completely elucidated. Here, we evaluated the effect of recombinant rat CC16 (rCC16) on the expression of tumor necrosis factor alpha (TNF-α), int...

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Bibliografiske detaljer
Udgivet i:Acta Biochim Biophys Sin (Shanghai)
Main Authors: Pang, Min, Yuan, Yangyang, Wang, Dong, Li, Ting, Wang, Dan, Shi, Xiaohong, Guo, Min, Wang, Chunfang, Zhang, Xinri, Zheng, Guoping, Yu, Baofeng, Wang, Hailong
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412021/
https://ncbi.nlm.nih.gov/pubmed/28338974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmx020
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