CXCR4 knockdown prevents inflammatory cytokine expression in macrophages by suppressing activation of MAPK and NF-κB signaling pathways

BACKGROUND: Recent evidence has shown that C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in acute lung injury (ALI). Macrophages are key factors in the pathogenesis of ALI. The aim of this study was to investigate the role of CXCR4 in macrophages after lipopolysaccharide (LPS) stimula...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Biosci
Hauptverfasser: Tian, Xue, Xie, Guogang, Xiao, Hui, Ding, Fengming, Bao, Wuping, Zhang, Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607528/
https://ncbi.nlm.nih.gov/pubmed/31304005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-019-0315-x
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