CXCR4 knockdown prevents inflammatory cytokine expression in macrophages by suppressing activation of MAPK and NF-κB signaling pathways

BACKGROUND: Recent evidence has shown that C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in acute lung injury (ALI). Macrophages are key factors in the pathogenesis of ALI. The aim of this study was to investigate the role of CXCR4 in macrophages after lipopolysaccharide (LPS) stimula...

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Vydáno v:Cell Biosci
Hlavní autoři: Tian, Xue, Xie, Guogang, Xiao, Hui, Ding, Fengming, Bao, Wuping, Zhang, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607528/
https://ncbi.nlm.nih.gov/pubmed/31304005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-019-0315-x
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