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ULK1‐mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn's mutant
Autophagy is a highly regulated catabolic pathway that is potently induced by stressors including starvation and infection. An essential component of the autophagy pathway is an ATG16L1‐containing E3‐like enzyme, which is responsible for lipidating LC3B and driving autophagosome formation. ATG16L1 p...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6607016/ https://ncbi.nlm.nih.gov/pubmed/31267703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846885 |
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