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ULK1‐mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn's mutant
Autophagy is a highly regulated catabolic pathway that is potently induced by stressors including starvation and infection. An essential component of the autophagy pathway is an ATG16L1‐containing E3‐like enzyme, which is responsible for lipidating LC3B and driving autophagosome formation. ATG16L1 p...
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| Pubblicato in: | EMBO Rep |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6607016/ https://ncbi.nlm.nih.gov/pubmed/31267703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846885 |
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