Oral Administration of Caffeine Exacerbates Cisplatin-Induced Hearing Loss

Adenosine A(1) receptors (A(1)AR) are well characterized for their role in cytoprotection. Previous studies have demonstrated the presence of these receptors in the cochlea where their activation were shown to suppress cisplatin-induced inflammatory response and the resulting ototoxicity. Inhibition...

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Pubblicato in:Sci Rep
Autori principali: Sheth, Sandeep, Sheehan, Kelly, Dhukhwa, Asmita, Al Aameri, Raheem F. H., Mamillapalli, Chaitanya, Mukherjea, Debashree, Rybak, Leonard P., Ramkumar, Vickram
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606569/
https://ncbi.nlm.nih.gov/pubmed/31267026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45964-9
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