Oral Administration of Caffeine Exacerbates Cisplatin-Induced Hearing Loss

Adenosine A(1) receptors (A(1)AR) are well characterized for their role in cytoprotection. Previous studies have demonstrated the presence of these receptors in the cochlea where their activation were shown to suppress cisplatin-induced inflammatory response and the resulting ototoxicity. Inhibition...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sheth, Sandeep, Sheehan, Kelly, Dhukhwa, Asmita, Al Aameri, Raheem F. H., Mamillapalli, Chaitanya, Mukherjea, Debashree, Rybak, Leonard P., Ramkumar, Vickram
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606569/
https://ncbi.nlm.nih.gov/pubmed/31267026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45964-9
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