Mechanisms of lymphoma clearance induced by high-dose alkylating agents

The extraordinary activity of high-dose cyclophosphamide against some high-grade lymphomas was described nearly 60 years ago. Here we address mechanisms that mediate cyclophosphamide activity in bona fide human double-hit lymphoma. We show that antibody resistance within the bone marrow (BM) is not...

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Udgivet i:Cancer Discov
Main Authors: Lossos, Chen, Liu, Yunpeng, Kolb, Kellie E., Christie, Amanda L., Van Scoyk, Alexandria, Prakadan, Sanjay M., Shigemori, Kay, Stevenson, Kristen E., Morrow, Sara, Plana, Olivia D., Fraser, Cameron, Jones, Kristen L., Liu, Huiyun, Pallasch, Christian P., Modiste, Rebecca, Nguyen, Quang-De, Craig, Jeffrey W., Morgan, Elizabeth A., Vega, Francisco, Aster, Jon C., Sarosiek, Kristopher A., Shalek, Alex K., Hemann, Michael T., Weinstock, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606344/
https://ncbi.nlm.nih.gov/pubmed/31040105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-1393
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