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Functional evaluation of variants of unknown significance in the BRCA2 gene identified in genetic testing
Heterozygous germline BRCA2 mutations predispose to breast, ovarian, pancreatic and other types of cancer. The presence of a pathogenic mutation in patients or their family members warrants close surveillance or prophylactic surgery. Besides clearly pathogenic mutations, variants leading only to a s...
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| Publicado no: | Cancer Biol Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6606029/ https://ncbi.nlm.nih.gov/pubmed/30638113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1550566 |
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