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The Makorin lep-2 and the lncRNA lep-5 regulate lin-28 to schedule sexual maturation of the C. elegans nervous system

Sexual maturation must occur on a controlled developmental schedule. In mammals, Makorin3 (MKRN3) and the miRNA regulators LIN28A/B are key regulators of this process, but how they act is unclear. In C. elegans, sexual maturation of the nervous system includes the functional remodeling of postmitoti...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lawson, Hannah, Vuong, Edward, Miller, Renee M, Kiontke, Karin, Fitch, David HA, Portman, Douglas S
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606027/
https://ncbi.nlm.nih.gov/pubmed/31264582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43660
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