Population Pharmacokinetics of Lopinavir/Ritonavir: Changes Across Formulations and Human Development from Infancy through Adulthood

Lopinavir/ritonavir (LPV/r) is recommended by the World Health Organization (WHO) as first-line treatment for HIV-infected infants and young children. We performed a composite population pharmacokinetic (PK) analysis on LPV plasma concentration data from six pediatric and adult studies to determine...

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Detaylı Bibliyografya
Yayımlandı:J Clin Pharmacol
Asıl Yazarlar: Yang, Jincheng, Nikanjam, Mina, Best, Brookie M., Pinto, Jorge, Chadwick, Ellen G., Daar, Eric S., Havens, Peter L., Rakhmanina, Natella, Capparelli, Edmund V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604805/
https://ncbi.nlm.nih.gov/pubmed/30252146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1293
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