Pharmacokinetics of Lopinavir/Ritonavir Crushed versus Whole Tablets in Children

OBJECTIVE: Lopinavir/ritonavir (Kaletra(®)) is first line therapy for pediatric HIV infection. In clinical practice, Kaletra(®) tablets are occasionally crushed for pediatric administration. This study compared lopinavir/ritonavir exposure between whole and crushed tablets in HIV-infected children....

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Hlavní autoři: Best, Brookie M., Capparelli, Edmund V., Diep, Huy, Rossi, Steven S., Farrell, Michael J., Williams, Elaine, Lee, Grace, van den Anker, John N., Rakhmanina, Natella
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205189/
https://ncbi.nlm.nih.gov/pubmed/21876444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318232b057
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