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Oxygen-dependent flow of sickle trait blood as an in vitro therapeutic benchmark for sickle cell disease treatments

Although homozygous sickle cell disease is often clinically severe, the corresponding heterozygous state, sickle cell trait, is almost completely benign despite the fact that there is only a modest difference in sickle hemoglobin levels between the two conditions. In both conditions, hypoxia can lea...

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Dettagli Bibliografici
Pubblicato in:Am J Hematol
Autori principali: Lu, Xinran, Chaudhury, Anwesha, Higgins, John M., Wood, David K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604607/
https://ncbi.nlm.nih.gov/pubmed/30033564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25227
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