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A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood

The pathology of sickle cell disease begins with the polymerization of intracellular hemoglobin under low oxygen tension, which leads to increased blood effective viscosity and vaso-occlusion. However, it has remained unclear how single-cell changes propagate up to the scale of bulk blood effective...

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Detalhes bibliográficos
Publicado no:APL Bioeng
Main Authors: Valdez, José M., Datta, Yvonne H., Higgins, John M., Wood, David K.
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881198/
https://ncbi.nlm.nih.gov/pubmed/31803859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5118212
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