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Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension

The majority of morbidity and mortality in sickle cell disease is caused by vaso-occlusion: circulatory obstruction leading to tissue ischemia and infarction. The consequences of vaso-occlusion are seen clinically throughout the vascular tree, from the relatively high-oxygen and high-velocity cerebr...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Lu, Xinran, Wood, David K., Higgins, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919586/
https://ncbi.nlm.nih.gov/pubmed/27332133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.050
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