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Oxygen-dependent flow of sickle trait blood as an in vitro therapeutic benchmark for sickle cell disease treatments

Although homozygous sickle cell disease is often clinically severe, the corresponding heterozygous state, sickle cell trait, is almost completely benign despite the fact that there is only a modest difference in sickle hemoglobin levels between the two conditions. In both conditions, hypoxia can lea...

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Bibliografiske detaljer
Udgivet i:Am J Hematol
Main Authors: Lu, Xinran, Chaudhury, Anwesha, Higgins, John M., Wood, David K.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604607/
https://ncbi.nlm.nih.gov/pubmed/30033564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25227
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