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Functional characterization of SMN evolution in mouse models of SMA

Spinal Muscular Atrophy (SMA) is a monogenic neurodegenerative disorder and the leading genetic cause of infantile mortality. While several functions have been ascribed to the SMN (survival motor neuron) protein, their specific contribution to the disease has yet to be fully elucidated. We hypothesi...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Osman, Erkan Y., Bolding, Madeline R., Villalón, Eric, Kaifer, Kevin A., Lorson, Zachary C., Tisdale, Sarah, Hao, Yue, Conant, Gavin C., Pires, J. Chris, Pellizzoni, Livio, Lorson, Christian L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603021/
https://ncbi.nlm.nih.gov/pubmed/31263170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45822-8
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