Functional characterization of SMN evolution in mouse models of SMA

Spinal Muscular Atrophy (SMA) is a monogenic neurodegenerative disorder and the leading genetic cause of infantile mortality. While several functions have been ascribed to the SMN (survival motor neuron) protein, their specific contribution to the disease has yet to be fully elucidated. We hypothesi...

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發表在:Sci Rep
Main Authors: Osman, Erkan Y., Bolding, Madeline R., Villalón, Eric, Kaifer, Kevin A., Lorson, Zachary C., Tisdale, Sarah, Hao, Yue, Conant, Gavin C., Pires, J. Chris, Pellizzoni, Livio, Lorson, Christian L.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603021/
https://ncbi.nlm.nih.gov/pubmed/31263170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45822-8
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