Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition

Nucleoplasmin (NP) is a pentameric histone chaperone that regulates the condensation state of chromatin in different cellular processes. We focus here on the interaction of NP with the histone octamer, showing that NP could bind sequentially the histone components to assemble an octamer-like particl...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Franco, Aitor, Arranz, Rocío, Fernández-Rivero, Noelia, Velázquez-Campoy, Adrián, Martín-Benito, Jaime, Segura, Joan, Prado, Adelina, Valpuesta, José M., Muga, Arturo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602930/
https://ncbi.nlm.nih.gov/pubmed/31263230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45726-7
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