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Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition

Nucleoplasmin (NP) is a pentameric histone chaperone that regulates the condensation state of chromatin in different cellular processes. We focus here on the interaction of NP with the histone octamer, showing that NP could bind sequentially the histone components to assemble an octamer-like particl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Franco, Aitor, Arranz, Rocío, Fernández-Rivero, Noelia, Velázquez-Campoy, Adrián, Martín-Benito, Jaime, Segura, Joan, Prado, Adelina, Valpuesta, José M., Muga, Arturo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602930/
https://ncbi.nlm.nih.gov/pubmed/31263230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45726-7
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