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Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition

Nucleoplasmin (NP) is a pentameric histone chaperone that regulates the condensation state of chromatin in different cellular processes. We focus here on the interaction of NP with the histone octamer, showing that NP could bind sequentially the histone components to assemble an octamer-like particl...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Franco, Aitor, Arranz, Rocío, Fernández-Rivero, Noelia, Velázquez-Campoy, Adrián, Martín-Benito, Jaime, Segura, Joan, Prado, Adelina, Valpuesta, José M., Muga, Arturo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602930/
https://ncbi.nlm.nih.gov/pubmed/31263230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45726-7
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