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Schlafen 3 knockout mice display gender-specific differences in weight gain, food efficiency, and expression of markers of intestinal epithelial differentiation, metabolism, and immune cell function

Self-renewal and differentiation are essential for intestinal epithelium absorptive functioning and adaptation to pathological states such as short gut syndrome, ulcers, and inflammatory bowel disease. The rodent Slfn3 and its human analog Slfn12 are critical in regulating intestinal epithelial diff...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vomhof-DeKrey, Emilie E., Lee, Jun, Lansing, Jack, Brown, Chris, Darland, Diane, Basson, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602453/
https://ncbi.nlm.nih.gov/pubmed/31260507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219267
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