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Schlafen12 Reduces the Aggressiveness of Triple Negative Breast Cancer through Post-Transcriptional Regulation of ZEB1 That Drives Stem Cell Differentiation

BACKGROUND/AIMS: Schlafen12 (SLFN12) promotes human intestinal and prostatic epithelial differentiation. We sought to determine whether SLFN12 reduces triple-negative breast cancer (TNBC) aggressiveness. METHODS: We validated bioinformatics analyses of publicly available databases by staining human...

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Bibliografiske detaljer
Udgivet i:Cell Physiol Biochem
Main Authors: Al-Marsoummi, Sarmad, Vomhof-DeKrey, Emilie, Basson, Marc D.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007982/
https://ncbi.nlm.nih.gov/pubmed/31838790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33594/000000191
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